Energized Protodermis was a sentient and very powerful substance.
Energized Protodermis was once located in the core of Spherus Magna, the home world of the Great Beings. Kept in the core for some time, it eventually leaked to the surface of the planet. When the Element Lords of the planet discovered its ability to transform or destroy, the Core War broke out. After noticing that Energized Protodermis was destroying the planet, the Great Beings began constructing the Mata Nui robot, and placed some of the substance inside, using it to stabilize the power source of the robot. After a major effort by the Fire Tribe to collect the Energized Protodermis for their own usage, the planet eventually shattered.
In the Matoran Universe, the substance eventually began to experiment on things around it, and offered its powers to those who it believed had intriguing intentions. It worked with the Makuta on their experiments, and to create Rahkshi, as it was interested in their work. Teridax constructed a pool of Energized Protodermis in his lair, and it often communicated with Teridax in one of his lairs to assist him with his experiments with various Rahi.
During their journey back to Metru Nui after the Great Cataclysm, the Toa Metru were blackmailed into retrieving a vial of Energized Protodermis for the Karzahni. They were informed of the pool of Energized Protodermis in one of Teridax's lairs, but when the Toa eventually arrived there the Energized Protodermis spoke to them.
Instead of allowing the Toa to take some of itself, the substance demonstrated its power by mutating a tiny insect into a 200-foot monster. It then watched as the Toa defended themselves against the beast, and when it tired of the fight it destroyed the insect. This led the Toa to attack the substance, which had made itself a physical form, and in response it began mutating a number of creatures into fierce monsters.
After the Toa defeated the creatures, they began taunting and angering the substance, eventually luring it into destroying the support pillars holding up the chamber. The Toa then attacked from all sides. Desperate to protect the pool, the substance was at a loss as to where to direct its attacks, since attacking one Toa would leave the pool open to damage from the others. With only one pillar remaining, the Toa halted and offered to leave the lair standing if they were allowed to take the Protodermis they came for and leave safely. The substance reluctantly agreed to let them take what they needed, but tried to attack them with a tidal wave of itself after they had collected the substance. The Toa quickly shattered the last pillar and collapsed the chamber, destroying the pool and escaping.
After a fight with the Bahrag, the Toa Mata descended into tubes filled with Energized Protodermis and were transformed into the Toa Nuva: more powerful versions of themselves with enhanced weapons, masks, armor and powers.
Later, Helryx and Keetongu arrived on an island to investigate the origins of several Rahkshi. They found the substance forming its physical form in the center of a giant lake of Energized Protodermis, and Helryx questioned the substance of its purpose and the destruction it had brought. When Helryx threatened that the Entity would be destroyed, the Entity replied by rousing a tidal wave of Energized Protodermis and rushing it towards the two beings. They escaped through a portal created by Vezon as the latter took their place. Vezon was then washed with Energized Protodermis, fusing him to the Kanohi Olmak he was wearing and granting him the power to create dimensional portals.
Energized Protodermis had the power to transform, fuse, or destroy, any object or creature it came into contact with, depending on the destiny of the one who came into contact with it.
- Destroying any object on contact.
- Transforming an object on contact, but only if said object is destined to transform.
- Transforming a Kraata into a Rahkshi on contact.
- Reverting the effect of Antidermis on contact.
- Fusing two beings if they came into contact with it together.
- Energized Protodermis was actually not at all a type of usual Protodermis; Usual Protodermis was artificially made by the Great Beings after the discovery of Energized Protodermis.
- Energized Protodermis was described as Mercury in the Mask of Light novelization.